Tumor-associated macrophage-derived exosomes promote EGFR-TKI resistance in non-small cell lung cancer by regulating the AKT, ERK1/2 and STAT3 signaling pathways

The evolutionary properties of organisms lead to the issue of targeted drug resistance. Numerous clinical trials have shown that tumor-associated macrophages (TAMs) in patients with lung cancer adversely affect the clinical efficacy of epithelial growth factor receptor (EGFR) tyrosine kinase inhibit...

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Detalles Bibliográficos
Autores principales: Yuan, Shiyang, Chen, Wenjun, Yang, Jian, Zheng, Yuanhai, Ye, Wen, Xie, Hui, Dong, Lie, Xie, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478622/
https://www.ncbi.nlm.nih.gov/pubmed/36168315
http://dx.doi.org/10.3892/ol.2022.13476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478622/
https://www.ncbi.nlm.nih.gov/pubmed/36168315
http://dx.doi.org/10.3892/ol.2022.13476

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