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Targeting inflammation and immune activation to improve CTLA4-Ig-based modulation of transplant rejection

For the last few decades, Calcineurin inhibitors (CNI)-based therapy has been the pillar of immunosuppression for prevention of organ transplant rejection. However, despite exerting effective control of acute rejection in the first year post-transplant, prolonged CNI use is associated with significa...

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Detalles Bibliográficos
Autores principales: Iglesias, Marcos, Brennan, Daniel C., Larsen, Christian P., Raimondi, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478663/
https://www.ncbi.nlm.nih.gov/pubmed/36119093
http://dx.doi.org/10.3389/fimmu.2022.926648