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Targeting inflammation and immune activation to improve CTLA4-Ig-based modulation of transplant rejection
For the last few decades, Calcineurin inhibitors (CNI)-based therapy has been the pillar of immunosuppression for prevention of organ transplant rejection. However, despite exerting effective control of acute rejection in the first year post-transplant, prolonged CNI use is associated with significa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478663/ https://www.ncbi.nlm.nih.gov/pubmed/36119093 http://dx.doi.org/10.3389/fimmu.2022.926648 |