Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance

Long noncoding RNAs (lncRNAs) play essential roles in the development and progression of many cancers. However, the contributions of lncRNAs to medulloblastoma (MB) remain poorly understood. Here, we identify Miat as an lncRNA enriched in the sonic hedgehog group of MB that is required for maintenan...

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Detalles Bibliográficos
Autores principales: Peng, Kai-Lin, Vasudevan, Harish N., Lockney, Dennis T., Baum, Rachel, Hendrickson, Ronald C., Raleigh, David R., Schmitt, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478675/
https://www.ncbi.nlm.nih.gov/pubmed/36067288
http://dx.doi.org/10.1073/pnas.2203738119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478675/
https://www.ncbi.nlm.nih.gov/pubmed/36067288
http://dx.doi.org/10.1073/pnas.2203738119

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