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Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance
Long noncoding RNAs (lncRNAs) play essential roles in the development and progression of many cancers. However, the contributions of lncRNAs to medulloblastoma (MB) remain poorly understood. Here, we identify Miat as an lncRNA enriched in the sonic hedgehog group of MB that is required for maintenan...
Autores principales: | Peng, Kai-Lin, Vasudevan, Harish N., Lockney, Dennis T., Baum, Rachel, Hendrickson, Ronald C., Raleigh, David R., Schmitt, Adam M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478675/ https://www.ncbi.nlm.nih.gov/pubmed/36067288 http://dx.doi.org/10.1073/pnas.2203738119 |
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