Cargando…

Convergent evolution of a genotoxic stress response in a parasite-specific p53 homolog

P53 is a widely studied tumor suppressor that plays important roles in cell-cycle regulation, cell death, and DNA damage repair. P53 is found throughout metazoans, even in invertebrates that do not develop malignancies. The prevailing theory for why these invertebrates possess a tumor suppressor is...

Descripción completa

Detalles Bibliográficos
Autores principales: Wendt, George R., Shiroor, Divya A., Adler, Carolyn E., Collins, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478680/
https://www.ncbi.nlm.nih.gov/pubmed/36067283
http://dx.doi.org/10.1073/pnas.2205201119