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Convergent evolution of a genotoxic stress response in a parasite-specific p53 homolog
P53 is a widely studied tumor suppressor that plays important roles in cell-cycle regulation, cell death, and DNA damage repair. P53 is found throughout metazoans, even in invertebrates that do not develop malignancies. The prevailing theory for why these invertebrates possess a tumor suppressor is...
Autores principales: | Wendt, George R., Shiroor, Divya A., Adler, Carolyn E., Collins, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478680/ https://www.ncbi.nlm.nih.gov/pubmed/36067283 http://dx.doi.org/10.1073/pnas.2205201119 |
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