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Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast
In natural populations, the same mutation can lead to different phenotypic outcomes due to the genetic variation that exists among individuals. Such genetic background effects are commonly observed, including in the context of many human diseases. However, systematic characterization of these effect...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478683/ https://www.ncbi.nlm.nih.gov/pubmed/36067306 http://dx.doi.org/10.1073/pnas.2204206119 |