Dimethyl fumarate attenuates pain behaviors in osteoarthritis rats via induction of Nrf2-mediated mitochondrial biogenesis

Osteoarthritis (OA), a chronic degenerative disease, leads to pain and loss of function. Existing treatments for OA pain have limited efficacy and show significant side effects. Dimethyl fumarate, a robust nuclear factor erythroid 2-related factor 2 (Nrf2) activator, could alleviate pain behaviors i...

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Detalles Bibliográficos
Autores principales: Gao, Shao-Jie, Li, Dan-Yang, Liu, Dai-Qiang, Sun, Jia, Zhang, Long-Qing, Wu, Jia-Yi, Song, Fan-He, Zhou, Ya-Qun, Mei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478692/
https://www.ncbi.nlm.nih.gov/pubmed/36065971
http://dx.doi.org/10.1177/17448069221124920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478692/
https://www.ncbi.nlm.nih.gov/pubmed/36065971
http://dx.doi.org/10.1177/17448069221124920

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