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Dimethyl fumarate attenuates pain behaviors in osteoarthritis rats via induction of Nrf2-mediated mitochondrial biogenesis

Osteoarthritis (OA), a chronic degenerative disease, leads to pain and loss of function. Existing treatments for OA pain have limited efficacy and show significant side effects. Dimethyl fumarate, a robust nuclear factor erythroid 2-related factor 2 (Nrf2) activator, could alleviate pain behaviors i...

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Detalles Bibliográficos
Autores principales:	Gao, Shao-Jie, Li, Dan-Yang, Liu, Dai-Qiang, Sun, Jia, Zhang, Long-Qing, Wu, Jia-Yi, Song, Fan-He, Zhou, Ya-Qun, Mei, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478692/ https://www.ncbi.nlm.nih.gov/pubmed/36065971 http://dx.doi.org/10.1177/17448069221124920

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