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[(68)Ga]Ga-PSMA PET/MRI, histological PSMA expression and preliminary experience with [(177)Lu]Lu-PSMA therapy in relapsing high-grade glioma

PURPOSE: High-grade gliomas (HGG) are still associated with a dismal prognosis. Prostate specific membrane antigen (PSMA) is discussed as a theranostic target for PSMA-directed radioligand therapy ([(177)Lu]Lu-PSMA RLT). Here, we report on the correlation of [(68)Ga]Ga-PSMA uptake with histological...

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Detalles Bibliográficos
Autores principales: Truckenmueller, Peter, Graef, Josefine, Scheel, Michael, Vajkoczy, Peter, Capper, David, Kaul, David, Furth, Christian, Amthauer, Holger, Brenner, Winfried, Onken, Julia Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478729/
https://www.ncbi.nlm.nih.gov/pubmed/36119502
http://dx.doi.org/10.3389/fonc.2022.980058