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Oocyte CTR1 is not essential for cisplatin-induced oocyte death of primordial follicle

Accumulated evidence indicates that cisplatin, a platinum-based alkylating agent, causes preferential DNA damage to oocytes of primordial follicles (PFs) in the ovary, suggesting oocyte-favored accumulation of cisplatin. Copper transporter 1 (CTR1; Slc31a1 ) is implicated in facilitating cisplatin u...

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Detalles Bibliográficos
Autores principales: Yu, Seok-Yeong, Luan, Yi, Abazarikia, Amirhossein, Dong, Rosemary, Lee, Jaekwon, Kim, So-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478746/
https://www.ncbi.nlm.nih.gov/pubmed/36120475
http://dx.doi.org/10.17912/micropub.biology.000632