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Genome architecture plasticity underlies DNA replication timing dynamics in cell differentiation

During the S-phase of eukaryotic cell cycle, DNA is replicated in a dedicatedly regulated temporal order, with regions containing active and inactive genes replicated early and late, respectively. Recent advances in sequencing technology allow us to explore the connection between replication timing...

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Detalles Bibliográficos
Autores principales: Yu, Wenjun, Zhong, Quan, Wen, Zi, Zhang, Weihan, Huang, Yanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478753/
https://www.ncbi.nlm.nih.gov/pubmed/36118849
http://dx.doi.org/10.3389/fgene.2022.961612