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Novel peptide-based vaccine targeting heat shock protein 90 induces effective antitumor immunity in a HER2+ breast cancer murine model

BACKGROUND: Heat shock protein 90 (HSP90) is a protein chaperone for most of the important signal transduction pathways in human epidermal growth factor receptor 2-positive (HER2+) breast cancer, including human epidermal growth factor receptor 2, estrogen receptor, progesterone receptor and Akt. Th...

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Detalles Bibliográficos
Autores principales: Kang, Jinho, Lee, Hye-Jin, Lee, Jimin, Hong, Jinhwa, Hong Kim, Yeul, Disis, Mary L, Gim, Jeong-An, Park, Kyong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478831/
https://www.ncbi.nlm.nih.gov/pubmed/36109084
http://dx.doi.org/10.1136/jitc-2022-004702