Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways

Although long-term survival in pediatric acute lymphoblastic leukemia (ALL) currently exceeds 90%, some subgroups, defined by specific genomic aberrations, respond poorly to treatment. We previously reported that leukemias harboring deletions or mutations affecting the B-cell transcription factor IK...

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Detalles Bibliográficos
Autores principales: Butler, Miriam, Vervoort, Britt M.T., van Ingen Schenau, Dorette S., Jongeneel, Lieneke, van der Zwet, Jordy C.G., Marke, René, Meijerink, Jules P.P., Scheijen, Blanca, van der Meer, Laurens T., van Leeuwen, Frank N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478899/
https://www.ncbi.nlm.nih.gov/pubmed/36119546
http://dx.doi.org/10.3389/fonc.2022.905665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478899/
https://www.ncbi.nlm.nih.gov/pubmed/36119546
http://dx.doi.org/10.3389/fonc.2022.905665

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