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Proton-induced DNA damage promotes integration of foreign plasmid DNA into human genome

High-risk human papillomaviruses (HPVs) cause virtually all cervical cancer cases and are also associated with other types of anogenital and oropharyngeal cancers. Normally, HPV exists as a circular episomal DNA in the infected cell. However, in some instances, it integrates into the human genome in...

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Detalles Bibliográficos
Autores principales: Katerji, Meghri, Bertucci, Antonella, Filippov, Valery, Vazquez, Marcelo, Chen, Xin, Duerksen-Hughes, Penelope J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478911/
https://www.ncbi.nlm.nih.gov/pubmed/36119491
http://dx.doi.org/10.3389/fonc.2022.928545