Transcriptomic changes in autophagy-related genes are inversely correlated with inflammation and are associated with multiple sclerosis lesion pathology

Autophagy is a lysosomal degradative pathway essential for maintaining cellular homeostasis and is also implicated in multiple aspects of both innate and adaptive immunity. Neuroinflammation, along with demyelination and axonal loss, is an important component of multiple sclerosis (MS). Induction of...

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Detalles Bibliográficos
Autores principales: Misrielal, Chairi, Alsema, Astrid M., Wijering, Marion H.C., Miedema, Anneke, Mauthe, Mario, Reggiori, Fulvio, Eggen, Bart J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478930/
https://www.ncbi.nlm.nih.gov/pubmed/36120103
http://dx.doi.org/10.1016/j.bbih.2022.100510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478930/
https://www.ncbi.nlm.nih.gov/pubmed/36120103
http://dx.doi.org/10.1016/j.bbih.2022.100510

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