Tyrosine 7.43 is important for mu-opioid receptor downstream signaling pathways activated by fentanyl

G protein–coupled receptors can signal through both G proteins and ß-arrestin2. For the µ-opioid receptor (MOR), early experimental evidence from a single study suggested that G protein signaling mediates analgesia and sedation, whereas ß-arrestin signaling mediates respiratory depression and consti...

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Detalles Bibliográficos
Autores principales: Tian, Xiangyun, Zhang, Junjie, Wang, Shaowen, Gao, Huan, Sun, Yi, Liu, Xiaoqian, Fu, Wei, Tan, Bo, Su, Ruibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478952/
https://www.ncbi.nlm.nih.gov/pubmed/36120357
http://dx.doi.org/10.3389/fphar.2022.919325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478952/
https://www.ncbi.nlm.nih.gov/pubmed/36120357
http://dx.doi.org/10.3389/fphar.2022.919325

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