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GANT61 exerts anticancer cell and anticancer stem cell capacity in colorectal cancer by blocking the Wnt/β-catenin and Notch signalling pathways

The present study aimed to assess the anticancer cell and anticancer stem cell (CSC) effects of GANT61, and its regulatory influence on the Wnt/β-catenin and Notch signalling pathways in colorectal cancer (CRC). HT-29 and HCT-116 cells were treated with 0, 2.5, 5, 10, 20 or 40 µM GANT61, after which...

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Detalles Bibliográficos
Autores principales: Si, Yanhui, Li, Lei, Zhang, Weiwei, Liu, Qiling, Liu, Baochi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478957/
https://www.ncbi.nlm.nih.gov/pubmed/36069229
http://dx.doi.org/10.3892/or.2022.8397