Nicotine self-administration and ERK signaling are altered in RasGRF2 knockout mice

Ras/Raf/MEK/ERK (Ras-ERK) signaling has been demonstrated to play a role in the effects of drugs of abuse such as cocaine and alcohol, but has not been extensively examined in nicotine-related reward behaviors. We examined the role of Ras Guanine Nucleotide Releasing Factor 2 (RasGRF2), an upstream...

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Detalles Bibliográficos
Autores principales: Morella, Ilaria, Pohořalá, Veronika, Calpe-López, Claudia, Brambilla, Riccardo, Spanagel, Rainer, Bernardi, Rick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479000/
https://www.ncbi.nlm.nih.gov/pubmed/36120353
http://dx.doi.org/10.3389/fphar.2022.986566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479000/
https://www.ncbi.nlm.nih.gov/pubmed/36120353
http://dx.doi.org/10.3389/fphar.2022.986566

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