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Nicotine self-administration and ERK signaling are altered in RasGRF2 knockout mice

Ras/Raf/MEK/ERK (Ras-ERK) signaling has been demonstrated to play a role in the effects of drugs of abuse such as cocaine and alcohol, but has not been extensively examined in nicotine-related reward behaviors. We examined the role of Ras Guanine Nucleotide Releasing Factor 2 (RasGRF2), an upstream...

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Detalles Bibliográficos
Autores principales:	Morella, Ilaria, Pohořalá, Veronika, Calpe-López, Claudia, Brambilla, Riccardo, Spanagel, Rainer, Bernardi, Rick E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479000/ https://www.ncbi.nlm.nih.gov/pubmed/36120353 http://dx.doi.org/10.3389/fphar.2022.986566

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