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Polg mtDNA mutator mice reveal limited involvement of vertebral bone loss in premature aging-related thoracolumbar hyperkyphosis

BACKGROUND: Age-related hyperkyphosis is multifactorial and involves alterations of vertebral bone, intervertebral discs (IVD) and paraspinal muscles. The relative contribution of these tissues remains unclear. Here, we compared differences in vertebral bone microarchitecture and IVD thickness betwe...

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Detalles Bibliográficos
Autores principales: Roessinger, Olivier, Hügle, Thomas, Walker, Ulrich A., Geurts, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479024/
https://www.ncbi.nlm.nih.gov/pubmed/36120646
http://dx.doi.org/10.1016/j.bonr.2022.101618