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Cryo-electron Microscopy of Adeno-associated Virus

[Image: see text] Adeno-associated virus (AAV) has a single-stranded DNA genome encapsidated in a small icosahedrally symmetric protein shell with 60 subunits. AAV is the leading delivery vector in emerging gene therapy treatments for inherited disorders, so its structure and molecular interactions...

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Detalles Bibliográficos
Autores principales: Stagg, Scott M., Yoshioka, Craig, Davulcu, Omar, Chapman, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479082/
https://www.ncbi.nlm.nih.gov/pubmed/35575684
http://dx.doi.org/10.1021/acs.chemrev.1c00936