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Ion channel Piezo1 activation promotes aerobic glycolysis in macrophages

Altered microenvironmental stiffness is a hallmark of inflammation. It is sensed by the mechanically activated cation channel Piezo1 in macrophages to induce subsequent immune responses. However, the mechanism by which the mechanosensitive signals shape the metabolic status of macrophages and tune i...

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Detalles Bibliográficos
Autores principales: Leng, Shaoqiu, Zhang, Xiaoyu, Wang, Shuwen, Qin, Jing, Liu, Qiang, Liu, Anli, Sheng, Zi, Feng, Qi, Hu, Xiang, Peng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479104/
https://www.ncbi.nlm.nih.gov/pubmed/36119083
http://dx.doi.org/10.3389/fimmu.2022.976482