Cargando…

Ion channel Piezo1 activation promotes aerobic glycolysis in macrophages

Altered microenvironmental stiffness is a hallmark of inflammation. It is sensed by the mechanically activated cation channel Piezo1 in macrophages to induce subsequent immune responses. However, the mechanism by which the mechanosensitive signals shape the metabolic status of macrophages and tune i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leng, Shaoqiu, Zhang, Xiaoyu, Wang, Shuwen, Qin, Jing, Liu, Qiang, Liu, Anli, Sheng, Zi, Feng, Qi, Hu, Xiang, Peng, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479104/ https://www.ncbi.nlm.nih.gov/pubmed/36119083 http://dx.doi.org/10.3389/fimmu.2022.976482

Ejemplares similares

Immune Checkpoint-Related Gene Polymorphisms Are Associated With Primary Immune Thrombocytopenia
por: Wang, Shuwen, et al.
Publicado: (2021)

Aerobic Glycolysis: Beyond Proliferation
por: Jones, William, et al.
Publicado: (2015)

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense
por: Krejčová, Gabriela, et al.
Publicado: (2019)

Physics of mechanotransduction by Piezo ion channels
por: Young, Michael, et al.
Publicado: (2022)

The role of macrophage ion channels in the progression of atherosclerosis
por: Wu, Xin, et al.
Publicado: (2023)

Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing
por: Atcha, Hamza, et al.
Publicado: (2021)

Piezo1 Channels as Force Sensors in Mechanical Force-Related Chronic Inflammation
por: Liu, Hailin, et al.
Publicado: (2022)

The emerging roles of piezo1 channels in animal models of multiple sclerosis
por: Yang, Kai, et al.
Publicado: (2022)

Mechanosensitive Piezo1 protein as a novel regulator in macrophages and macrophage-mediated inflammatory diseases
por: Tang, Yu, et al.
Publicado: (2023)

Crosstalk Between CD11b and Piezo1 Mediates Macrophage Responses to Mechanical Cues
por: Atcha, Hamza, et al.
Publicado: (2021)

Deciphering transcriptome alterations in bone marrow hematopoiesis at single-cell resolution in immune thrombocytopenia
por: Liu, Yan, et al.
Publicado: (2022)

Immunoregulatory Role of the Mechanosensitive Ion Channel Piezo1 in Inflammation and Cancer
por: Wang, Yuexin, et al.
Publicado: (2022)

Mechanosensitive Piezo1 and Piezo2 ion channels in craniofacial development and dentistry: Recent advances and prospects
por: Lin, Yifan, et al.
Publicado: (2022)

Macrophages induce gingival destruction via Piezo1-mediated MMPs-degrading collagens in periodontitis
por: Zhao, Tong, et al.
Publicado: (2023)

Piezo1 ion channels inherently function as independent mechanotransducers
por: Lewis, Amanda H, et al.
Publicado: (2021)

The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation
por: Zhu, Jiejun, et al.
Publicado: (2023)

Function of TRP channels in monocytes/macrophages
por: Wu, Jiangbo, et al.
Publicado: (2023)

The Function of the Novel Mechanical Activated Ion Channel Piezo1 in the Human Osteosarcoma Cells
por: Jiang, Long, et al.
Publicado: (2017)

Human PIEZO1 Ion Channel Functions as a Split Protein
por: Bae, Chilman, et al.
Publicado: (2016)

Chondroprotection by urocortin involves blockade of the mechanosensitive ion channel Piezo1
por: Lawrence, K. M., et al.
Publicado: (2017)

Mechanosensitive ion channels in apoptosis and ferroptosis: focusing on the role of Piezo1
por: Kim, Yong-Jae, et al.
Publicado: (2023)

Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance
por: Zhao, Can, et al.
Publicado: (2019)

P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis
por: de Salles, Érika Machado, et al.
Publicado: (2023)

The Role of Mechanically-Activated Ion Channels Piezo1, Piezo2, and TRPV4 in Chondrocyte Mechanotransduction and Mechano-Therapeutics for Osteoarthritis
por: Gao, Winni, et al.
Publicado: (2022)

Piezo channels in the urinary system
por: Li, Xu, et al.
Publicado: (2022)

Mechanisms of PIEZO Channel Inactivation
por: Zhou, Zijing, et al.
Publicado: (2023)

Piezo1 ion channel pore properties are dictated by C-terminal region
por: Coste, Bertrand, et al.
Publicado: (2015)

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
por: Nonomura, Keiko, et al.
Publicado: (2018)

The Piezo2 ion channel is mechanically activated by low-threshold positive pressure
por: Shin, Kyung Chul, et al.
Publicado: (2019)

Formation and Function of Mammalian Epithelia: Roles for Mechanosensitive PIEZO1 Ion Channels
por: Stewart, Teneale A., et al.
Publicado: (2019)

The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia
por: Zhu, Ting, et al.
Publicado: (2023)

Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages
por: Drummer, Charles, et al.
Publicado: (2023)

“Immuno-Transient Receptor Potential Ion Channels”: The Role in Monocyte- and Macrophage-Mediated Inflammatory Responses
por: Santoni, Giorgio, et al.
Publicado: (2018)

A rare case with compound heterozygous mutations of piezo-type mechanosensitive ion channel component 2 (PIEZO2) induced tracheobronchomalacia
por: Wu, Juan, et al.
Publicado: (2021)

Novel factor VII gene mutations in six families with hereditary coagulation factor VII deficiency
por: Zhang, Xiaoyu, et al.
Publicado: (2021)

Unsupervised Idealization of Ion Channel Recordings by Minimum Description Length: Application to Human PIEZO1-Channels
por: Gnanasambandam, Radhakrishnan, et al.
Publicado: (2017)

Aerobic glycolysis, motility, and cytoskeletal remodeling
por: Verdone, James E, et al.
Publicado: (2015)

WWOX loss activates aerobic glycolysis
por: Abu-Remaileh, Muhannad, et al.
Publicado: (2014)

Proton export upregulates aerobic glycolysis
por: Russell, Shonagh, et al.
Publicado: (2022)

NCAPG stimulates lung adenocarcinoma cell stemness through aerobic glycolysis
por: Zhang, Zuwang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h6i183o2jbpm2e7ssr030i5vg2