Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats

Cannabidiol (CBD) presents antiparkinsonian properties and neuromodulatory effects, possibly due to the pleiotropic activity caused at multiple molecular targets. Recently, the GPR55 receptor has emerged as a molecular target of CBD. Interestingly, GPR55 mRNA is expressed in the external globus pall...

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Detalles Bibliográficos
Autores principales: Patricio, Felipe, Morales Dávila, Eliud, Patricio-Martínez, Aleidy, Arana Del Carmen, Nayeli, Martínez, Isabel, Aguilera, José, Perez-Aguilar, Jose Manuel, Limón, Ilhuicamina Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479130/
https://www.ncbi.nlm.nih.gov/pubmed/36120297
http://dx.doi.org/10.3389/fphar.2022.945836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479130/
https://www.ncbi.nlm.nih.gov/pubmed/36120297
http://dx.doi.org/10.3389/fphar.2022.945836

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