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Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats
Cannabidiol (CBD) presents antiparkinsonian properties and neuromodulatory effects, possibly due to the pleiotropic activity caused at multiple molecular targets. Recently, the GPR55 receptor has emerged as a molecular target of CBD. Interestingly, GPR55 mRNA is expressed in the external globus pall...
Autores principales: | Patricio, Felipe, Morales Dávila, Eliud, Patricio-Martínez, Aleidy, Arana Del Carmen, Nayeli, Martínez, Isabel, Aguilera, José, Perez-Aguilar, Jose Manuel, Limón, Ilhuicamina Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479130/ https://www.ncbi.nlm.nih.gov/pubmed/36120297 http://dx.doi.org/10.3389/fphar.2022.945836 |
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