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Effect of safranal on the response of cancer cells to topoisomerase I inhibitors: Does sequence matter?
Lung and colorectal cancers are among the leading causes of death from cancer worldwide. Although topotecan (TPT), a topoisomerase1 inhibitor, is a first- and second-line drug for lung and colon cancers, the development of drug resistance and toxicity still remain as a major obstacle to chemotherape...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479137/ https://www.ncbi.nlm.nih.gov/pubmed/36120345 http://dx.doi.org/10.3389/fphar.2022.938471 |