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Effect of safranal on the response of cancer cells to topoisomerase I inhibitors: Does sequence matter?

Lung and colorectal cancers are among the leading causes of death from cancer worldwide. Although topotecan (TPT), a topoisomerase1 inhibitor, is a first- and second-line drug for lung and colon cancers, the development of drug resistance and toxicity still remain as a major obstacle to chemotherape...

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Detalles Bibliográficos
Autores principales: Lozon, Lama, Saleh, Ekram, Menon, Varsha, Ramadan, Wafaa S., Amin, Amr, El-Awady, Raafat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479137/
https://www.ncbi.nlm.nih.gov/pubmed/36120345
http://dx.doi.org/10.3389/fphar.2022.938471