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Not sorcery after all: Roles of multiple charged residues in membrane insertion of gasdermin-A3

Gasdermins execute programmatory cell death, known as pyroptosis, by forming medium-sized membrane pores. Recently, the molecular structure of those pores as well as the diversity in their shape and size have been revealed by cryoTEM and atomic force microscopy, respectively. Even though a growth of...

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Detalles Bibliográficos
Autores principales: Korn, Viktoria, Pluhackova, Kristyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479151/
https://www.ncbi.nlm.nih.gov/pubmed/36120563
http://dx.doi.org/10.3389/fcell.2022.958957