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Simulations of DNA-Origami Self-Assembly Reveal Design-Dependent Nucleation Barriers

[Image: see text] Nucleation is the rate-determining step in the kinetics of many self-assembly processes. However, the importance of nucleation in the kinetics of DNA-origami self-assembly, which involves both the binding of staple strands and the folding of the scaffold strand, is unclear. Here, u...

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Detalles Bibliográficos
Autores principales: Cumberworth, Alexander, Frenkel, Daan, Reinhardt, Aleks
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479157/
https://www.ncbi.nlm.nih.gov/pubmed/36037484
http://dx.doi.org/10.1021/acs.nanolett.2c01372