A novel gene signature unveils three distinct immune-metabolic rewiring patterns conserved across diverse tumor types and associated with outcomes

Existing immune signatures and tumor mutational burden have only modest predictive capacity for the efficacy of immune check point inhibitors. In this study, we developed an immune-metabolic signature suitable for personalized ICI therapies. A classifier using an immune-metabolic signature (IMMETCOL...

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Detalles Bibliográficos
Autores principales: Pedrosa, Leire, Foguet, Carles, Oliveres, Helena, Archilla, Iván, de Herreros, Marta García, Rodríguez, Adela, Postigo, Antonio, Benítez-Ribas, Daniel, Camps, Jordi, Cuatrecasas, Miriam, Castells, Antoni, Prat, Aleix, Thomson, Timothy M., Maurel, Joan, Cascante, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479210/
https://www.ncbi.nlm.nih.gov/pubmed/36119118
http://dx.doi.org/10.3389/fimmu.2022.926304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479210/
https://www.ncbi.nlm.nih.gov/pubmed/36119118
http://dx.doi.org/10.3389/fimmu.2022.926304

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