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Integrated multi-omics reveals the activated retinal microglia with intracellular metabolic reprogramming contributes to inflammation in STZ-induced early diabetic retinopathy

Diabetic retinopathy (DR) is the leading cause of visual impairment and blindness among working-age people. Inflammation is recognized as a critical driver of the DR process. However, the main retina-specific cell type producing pro-inflammatory cytokines and its mechanism underlying DR are still un...

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Detalles Bibliográficos
Autores principales: Lv, Kangjia, Ying, Hui, Hu, Guangyi, Hu, Jing, Jian, Qizhi, Zhang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479211/
https://www.ncbi.nlm.nih.gov/pubmed/36119084
http://dx.doi.org/10.3389/fimmu.2022.942768