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Role of DNA dioxygenase Ten-Eleven translocation 3 (TET3) in rheumatoid arthritis progression

BACKGROUND: Rheumatoid arthritis (RA) patients present with abnormal methylation patterns in their fibroblast-like synoviocytes (FLS). Given that DNA demethylation is critical for producing DNA methylation patterns, we hypothesized that DNA demethylation may facilitate RA progression. Therefore, we...

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Detalles Bibliográficos
Autores principales: Kawabe, Akio, Yamagata, Kaoru, Kato, Shigeaki, Nakano, Kazuhisa, Sakata, Kei, Tsukada, Yu-ichi, Ohmura, Koichiro, Nakayamada, Shingo, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479255/
https://www.ncbi.nlm.nih.gov/pubmed/36114544
http://dx.doi.org/10.1186/s13075-022-02908-5