Biomimetic Total Synthesis and Investigation of the Non‐Enzymatic Chemistry of Oxazinin A

We report the first total synthesis of an antimycobacterial natural product oxazinin A that takes advantage of a multi‐component cascade reaction of anthranilic acid and a precursor polyketide containing an aldehyde. The route utilized for the synthesis of the pseudodimeric oxazinin A validates a pr...

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Detalles Bibliográficos
Autores principales: Aniebok, Victor, Shingare, Rahul D., Wei‐Lee, Hsiau, Johnstone, Timothy C., MacMillan, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479274/
https://www.ncbi.nlm.nih.gov/pubmed/35881566
http://dx.doi.org/10.1002/anie.202208029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479274/
https://www.ncbi.nlm.nih.gov/pubmed/35881566
http://dx.doi.org/10.1002/anie.202208029

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