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Biomimetic Total Synthesis and Investigation of the Non‐Enzymatic Chemistry of Oxazinin A
We report the first total synthesis of an antimycobacterial natural product oxazinin A that takes advantage of a multi‐component cascade reaction of anthranilic acid and a precursor polyketide containing an aldehyde. The route utilized for the synthesis of the pseudodimeric oxazinin A validates a pr...
Autores principales: | Aniebok, Victor, Shingare, Rahul D., Wei‐Lee, Hsiau, Johnstone, Timothy C., MacMillan, John B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479274/ https://www.ncbi.nlm.nih.gov/pubmed/35881566 http://dx.doi.org/10.1002/anie.202208029 |
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