Cargando…

Adiponectin reduces apoptosis of diabetic cardiomyocytes by regulating miR-711/TLR4 axis

OBJECTIVE: To investigate the regulation of adiponectin/miR-711 on TLR4/NF-κB-mediated inflammatory response and diabetic cardiomyocyte apoptosis. METHODS: Diabetes models were established using rats and H9c2 cardiomyocytes. qRT-PCR was used to detect adiponectin, miR-711, and TLR4. MTT, β-galactosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zuo, Yu, Xiao, Tao, Qiu, Xiangdong, Liu, Zuoliang, Zhang, Shengnan, Zhou, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479314/
https://www.ncbi.nlm.nih.gov/pubmed/36114541
http://dx.doi.org/10.1186/s13098-022-00904-y