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Adiponectin reduces apoptosis of diabetic cardiomyocytes by regulating miR-711/TLR4 axis
OBJECTIVE: To investigate the regulation of adiponectin/miR-711 on TLR4/NF-κB-mediated inflammatory response and diabetic cardiomyocyte apoptosis. METHODS: Diabetes models were established using rats and H9c2 cardiomyocytes. qRT-PCR was used to detect adiponectin, miR-711, and TLR4. MTT, β-galactosi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479314/ https://www.ncbi.nlm.nih.gov/pubmed/36114541 http://dx.doi.org/10.1186/s13098-022-00904-y |