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ICOS-Fc as innovative immunomodulatory approach to counteract inflammation and organ injury in sepsis
Inducible T cell co-stimulator (ICOS), an immune checkpoint protein expressed on activated T cells and its unique ligand, ICOSL, which is expressed on antigen-presenting cells and non-hematopoietic cells, have been extensively investigated in the immune response. Recent findings showed that a solubl...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479331/ https://www.ncbi.nlm.nih.gov/pubmed/36119089 http://dx.doi.org/10.3389/fimmu.2022.992614 |