A potent synthetic nanobody with broad-spectrum activity neutralizes SARS-CoV-2 virus and the Omicron variant BA.1 through a unique binding mode

The major challenge to controlling the COVID pandemic is the rapid mutation rate of the SARS-CoV-2 virus, leading to the escape of the protection of vaccines and most of the neutralizing antibodies to date. Thus, it is essential to develop neutralizing antibodies with broad-spectrum activity targeti...

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Detalles Bibliográficos
Autores principales: Zhao, Dongping, Liu, Liqin, Liu, Xinlin, Zhang, Jinlei, Yin, Yuqing, Luan, Linli, Jiang, Dingwen, Yang, Xiong, Li, Lei, Xiong, Hualong, Xing, Dongming, Zheng, Qingbing, Xia, Ningshao, Tao, Yuyong, Li, Shaowei, Huang, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479348/
https://www.ncbi.nlm.nih.gov/pubmed/36109732
http://dx.doi.org/10.1186/s12951-022-01619-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479348/
https://www.ncbi.nlm.nih.gov/pubmed/36109732
http://dx.doi.org/10.1186/s12951-022-01619-y

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