Genetic regulation of RNA splicing in human pancreatic islets

BACKGROUND: Non-coding genetic variants that influence gene transcription in pancreatic islets play a major role in the susceptibility to type 2 diabetes (T2D), and likely also contribute to type 1 diabetes (T1D) risk. For many loci, however, the mechanisms through which non-coding variants influenc...

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Detalles Bibliográficos
Autores principales: Atla, Goutham, Bonàs-Guarch, Silvia, Cuenca-Ardura, Mirabai, Beucher, Anthony, Crouch, Daniel J. M., Garcia-Hurtado, Javier, Moran, Ignasi, Irimia, Manuel, Prasad, Rashmi B., Gloyn, Anna L., Marselli, Lorella, Suleiman, Mara, Berney, Thierry, de Koning, Eelco J. P., Kerr-Conte, Julie, Pattou, Francois, Todd, John A., Piemonti, Lorenzo, Ferrer, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479353/
https://www.ncbi.nlm.nih.gov/pubmed/36109769
http://dx.doi.org/10.1186/s13059-022-02757-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479353/
https://www.ncbi.nlm.nih.gov/pubmed/36109769
http://dx.doi.org/10.1186/s13059-022-02757-0

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