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Cannabinoid signaling and risk in Huntington's disease

Dysregulated endocannabinoid (eCB) signaling and the loss of cannabinoid receptors (CB1Rs) are important phenotypes of Huntington's disease (HD) but the precise contribution that eCB signaling has at the circuit level is unknown. Using a computational model of spiking neurons, synapses, and eCB...

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Detalles Bibliográficos
Autores principales: Humble, James, Kozloski, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479462/
https://www.ncbi.nlm.nih.gov/pubmed/36118134
http://dx.doi.org/10.3389/fncom.2022.903947