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Correlation between KRAS, NRAS and BRAF mutations and tumor localizations in patients with primary and metastatic colorectal cancer

INTRODUCTION: Detection of abnormalities in the KRAS, NRAS and BRAF genes is extremely important for proper qualification of colorectal cancer (CRC) patients for therapy with anti-EGFR (epidermal growth factor receptor) monoclonal antibodies. However, data about prevalence of mutations in these gene...

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Detalles Bibliográficos
Autores principales: Bożyk, Aleksandra, Krawczyk, Paweł, Reszka, Katarzyna, Krukowska, Kinga, Kolak, Agnieszka, Mańdziuk, Sławomir, Wojas-Krawczyk, Kamila, Ramlau, Rodryg, Milanowski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479594/
https://www.ncbi.nlm.nih.gov/pubmed/36160343
http://dx.doi.org/10.5114/aoms/109170