Functional cure of hepatitis B requires silencing covalently closed circular and integrated hepatitis B virus DNA

Chronic hepatitis B virus (HBV) infection remains a major global health problem. Hepatitis B surface antigen (HBsAg) loss has been accepted as the definition of a functional HBV cure. Recent studies found that while covalently closed circular DNA (cccDNA) is the predominant source of HBsAg in hepati...

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Detalles Bibliográficos
Autores principales: Ghany, Marc G., Lok, Anna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479618/
https://www.ncbi.nlm.nih.gov/pubmed/36106633
http://dx.doi.org/10.1172/JCI163175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479618/
https://www.ncbi.nlm.nih.gov/pubmed/36106633
http://dx.doi.org/10.1172/JCI163175

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