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DAP5 drives translation of specific mRNA targets with upstream ORFs in human embryonic stem cells

Death associated protein 5 (DAP5/eIF4G2/NAT1) is a member of the eIF4G translation initiation factors that has been shown to mediate noncanonical and/or cap-independent translation. It is essential for embryonic development and for differentiation of embryonic stem cells (ESCs), specifically its abi...

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Detalles Bibliográficos
Autores principales: David, Maya, Olender, Tsviya, Mizrahi, Orel, Weingarten-Gabbay, Shira, Friedlander, Gilgi, Meril, Sara, Goldberg, Nadav, Savidor, Alon, Levin, Yishai, Salomon, Vered, Stern-Ginossar, Noam, Bialik, Shani, Kimchi, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479741/
https://www.ncbi.nlm.nih.gov/pubmed/35961752
http://dx.doi.org/10.1261/rna.079194.122