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CMTr mediated 2′-O-ribose methylation status of cap-adjacent nucleotides across animals

Cap methyltransferases (CMTrs) O methylate the 2′ position of the ribose (cOMe) of cap-adjacent nucleotides of animal, protist, and viral mRNAs. Animals generally have two CMTrs, whereas trypanosomes have three, and many viruses encode one in their genome. In the splice leader of mRNAs in trypanosom...

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Detalles Bibliográficos
Autores principales: Dix, Thomas C., Haussmann, Irmgard U., Brivio, Sarah, Nallasivan, Mohannakarthik P., HadzHiev, Yavor, Müller, Ferenc, Müller, Berndt, Pettitt, Jonathan, Soller, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479742/
https://www.ncbi.nlm.nih.gov/pubmed/35970556
http://dx.doi.org/10.1261/rna.079317.122