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Original compound with anticonvulsant activity in the treatment of alcoholism

INTRODUCTION: Original compound ortho-fluorobenzonal, a barbiturate derivative, is shown to reveal strong anticonvulsant activity by means increasing GABA-mediation. Disturbance of GABA(A) -receptors functions play an essential role in both alcoholism and epilepsy pathogenesis. OBJECTIVES: Taking in...

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Detalles Bibliográficos
Autores principales: Markova, E., Savkin, I., Knyazheva, M., Shushpanova, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479971/
http://dx.doi.org/10.1192/j.eurpsy.2021.2171