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Self-assembling protein nanoparticles and virus like particles correctly display β-barrel from meningococcal factor H-binding protein through genetic fusion

Recombinant protein-based vaccines are a valid and safer alternative to traditional vaccines based on live-attenuated or killed pathogens. However, the immune response of subunit vaccines is generally lower compared to that elicited by traditional vaccines and usually requires the use of adjuvants....

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Detalles Bibliográficos
Autores principales: Cappelli, Luigia, Cinelli, Paolo, Giusti, Fabiola, Ferlenghi, Ilaria, Utrio-Lanfaloni, Sabrina, Wahome, Newton, Bottomley, Matthew James, Maione, Domenico, Cozzi, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480994/
https://www.ncbi.nlm.nih.gov/pubmed/36112575
http://dx.doi.org/10.1371/journal.pone.0273322