Cargando…
Self-assembling protein nanoparticles and virus like particles correctly display β-barrel from meningococcal factor H-binding protein through genetic fusion
Recombinant protein-based vaccines are a valid and safer alternative to traditional vaccines based on live-attenuated or killed pathogens. However, the immune response of subunit vaccines is generally lower compared to that elicited by traditional vaccines and usually requires the use of adjuvants....
Autores principales: | Cappelli, Luigia, Cinelli, Paolo, Giusti, Fabiola, Ferlenghi, Ilaria, Utrio-Lanfaloni, Sabrina, Wahome, Newton, Bottomley, Matthew James, Maione, Domenico, Cozzi, Roberta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9480994/ https://www.ncbi.nlm.nih.gov/pubmed/36112575 http://dx.doi.org/10.1371/journal.pone.0273322 |
Ejemplares similares
-
Moraxella catarrhalis evades neutrophil oxidative stress responses providing a safer niche for nontypeable Haemophilus influenzae
por: Nicchi, Sonia, et al.
Publicado: (2022) -
Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H-binding protein
por: Peschiera, Ilaria, et al.
Publicado: (2019) -
Effective Multivalent Oriented Presentation of Meningococcal NadA Antigen Trimers by Self-Assembling Ferritin Nanoparticles
por: Veggi, Daniele, et al.
Publicado: (2023) -
Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096
por: Veggi, Daniele, et al.
Publicado: (2022) -
Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6
por: Bianchi, Federica, et al.
Publicado: (2019)