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Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model

Recent studies suggest that ultra-high dose rates of proton radiation (>40 Gy/s; FLASH) confer less toxicity to exposed healthy tissue and reduce cognitive decline compared with conventional radiation dose rates (~1 Gy/s), but further preclinical data are required to demonstrate this sparing effe...

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Detalles Bibliográficos
Autores principales: Williams, Michael T., Sugimoto, Chiho, Regan, Samantha L., Pitzer, Emily M., Fritz, Adam L., Sertorio, Mathieu, Mascia, Anthony E., Vatner, Ralph E., Perentesis, John P., Vorhees, Charles V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481014/
https://www.ncbi.nlm.nih.gov/pubmed/36112695
http://dx.doi.org/10.1371/journal.pone.0274007