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FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution

BACKGROUND AND AIMS: Stomach cells can be converted to insulin-producing cells by Neurog3, MafA, and Pdxl over-expression. Enteroendocrine cells can be similarly made to produce insulin by the deletion of FOXO1. Characteristics and functional properties of FOXO1-expressing stomach cells are not know...

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Detalles Bibliográficos
Autores principales: McKimpson, Wendy M., Kuo, Taiyi, Kitamoto, Takumi, Higuchi, Sei, Mills, Jason C., Haeusler, Rebecca A., Accili, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481069/
https://www.ncbi.nlm.nih.gov/pubmed/36117550
http://dx.doi.org/10.1016/j.gastha.2022.05.005