Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals

The binding of the SARS-CoV-2 spike to angiotensin-converting enzyme 2 (ACE2) promotes virus entry into the cell. Targeting this interaction represents a promising strategy to generate antivirals. By screening a phage-display library of biosynthetic protein sequences build on a rigid alpha-helicoida...

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Detalles Bibliográficos
Autores principales: Thébault, Stéphanie, Lejal, Nathalie, Dogliani, Alexis, Donchet, Amélie, Urvoas, Agathe, Valerio-Lepiniec, Marie, Lavie, Muriel, Baronti, Cécile, Touret, Franck, Da Costa, Bruno, Bourgon, Clara, Fraysse, Audrey, Saint-Albin-Deliot, Audrey, Morel, Jessica, Klonjkowski, Bernard, de Lamballerie, Xavier, Dubuisson, Jean, Roussel, Alain, Minard, Philippe, Le Poder, Sophie, Meunier, Nicolas, Delmas, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481167/
https://www.ncbi.nlm.nih.gov/pubmed/36067253
http://dx.doi.org/10.1371/journal.ppat.1010799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481167/
https://www.ncbi.nlm.nih.gov/pubmed/36067253
http://dx.doi.org/10.1371/journal.ppat.1010799

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