Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model

Understanding the host pathways that define susceptibility to Severe-acute-respiratory-syndrome-coronavirus-2 (SARS-CoV-2) infection and disease are essential for the design of new therapies. Oxygen levels in the microenvironment define the transcriptional landscape, however the influence of hypoxia...

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Detalles Bibliográficos
Autores principales: Wing, Peter A. C., Prange-Barczynska, Maria, Cross, Amy, Crotta, Stefania, Orbegozo Rubio, Claudia, Cheng, Xiaotong, Harris, James M., Zhuang, Xiaodong, Johnson, Rachel L., Ryan, Kathryn A., Hall, Yper, Carroll, Miles W., Issa, Fadi, Balfe, Peter, Wack, Andreas, Bishop, Tammie, Salguero, Francisco J., McKeating, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481176/
https://www.ncbi.nlm.nih.gov/pubmed/36067210
http://dx.doi.org/10.1371/journal.ppat.1010807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9481176/
https://www.ncbi.nlm.nih.gov/pubmed/36067210
http://dx.doi.org/10.1371/journal.ppat.1010807

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